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Louisville and Kentucky at some point in the last 20 years became one of the best rivalries in college basketball. One has owned the SEC for years (for the most part). And the other, the ACC (again, for the most part).
Both have a national championship win in the last 5 years. Both have made the final four several times in the last 10 years. And the teams, and fans, apparently hate each other.
How Kentucky and Louisville embraced the hate in college basketball's most heated rivalry
I never knew how deep the hate went between these two team's coaches (Pitino v Calipari in current form), the fans, the towns, hell even the states, over a rivalry that seems to have culminated specifically into college basketball. If you are a fan of either of these teams, I recommend checking this article out, if you don't know the history of the rivalry. Interesting stuff.
..I fall on the side of Kentucky.